A 5-day-old newborn boy has no discharge of meconium (original feces) at the clypeus of the anus. The probe cannot be inserted into the anus. There is an admixture of feces in the urine. What pathology can be suspected in this child? What is the reason for the formation of this malformation?
Atresia of the anus and, possibly, of the rectum, arose as a result of the retention of cells filling the digestive tube during embryogenesis. An admixture of feces in the urine indicates the presence of a fistula, the occurrence of which is associated with impaired proliferation, differentiation, adhesion and cell movement.
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