How does nicotine in tobacco smoke affect the circulatory and nervous systems?

Having sucked into the blood, nicotine affects the nerve nodes that regulate the functioning of the heart and blood vessels. At first, they stimulate the work of these centers, and then slow down. As a result, frequent heartbeats begin, accompanied by interruptions in cardiac activity. There is a narrowing of the vessels of the heart and legs. The consequence of this is heart attacks and intermittent claudication – sharp spasms of the vessels of the legs, because of which it is impossible to continue the movement. We have to wait until they pass and blood circulation will be restored. In advanced cases, gangrene develops, and the leg has to be amputated. Due to the narrowing of the cerebral vessels, memory is reduced. The subjective feeling of vigor and increased efficiency does not last long, then it is replaced by drowsiness, which the smoker is trying to remove with a new portion of tobacco smoke. But since this can by no means always be done, an unmet need for tobacco arises, due to which a person cannot concentrate on anything else.

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