How does the enzyme activity change depending on the pH of the medium? Why do enzymes work mainly in an environment

How does the enzyme activity change depending on the pH of the medium? Why do enzymes work mainly in an environment that is close to neutral, and not in acidic or alkaline environments? What enzymes are active in an acidic environment?

The pH of the medium also affects the activity of the enzyme and the reaction rate.
Enzymes are active at different concentrations of H + and OH ions. Most of them work effectively within narrow pH ranges, more often in a neutral environment. A shift in the concentration of hydrogen ions can change the electric charge of the protein-enzyme, which will lead to a change in the configuration of the molecule and a decrease in activity.

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