The activity of the kidneys is controlled by both the nervous and humoral regulatory mechanisms. When the sympathetic department of the autonomic nervous system is excited, the blood vessels of the kidneys narrow, the volume of blood flowing through them decreases and, as a result, the formation of primary urine decreases. The formation of urine is affected by pituitary hormones (vasopressin), adrenal glands (aldosterone), other glands and the kidneys themselves
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