How is respiration regulated in the human body?

Respiration is regulated by humoral and nervous mechanisms. An excess of carbon dioxide in the air and intercellular substance accelerates the depth and frequency of breathing, adrenaline and some other hormones have the same effect. Involuntary nerve regulation is carried out by the respiratory center of the medulla oblongata, while the effect on cold and pain receptors stops breathing. Voluntary regulation depends on the activity of the cerebral hemispheres, i.e., a person can consciously speed up or slow down the respiratory rhythm in some situations.