In humans, Marfan’s syndrome, accompanied by an abnormality in the development of connective tissue, is inherited as an autosomal
September 14, 2020 | Education
| In humans, Marfan’s syndrome, accompanied by an abnormality in the development of connective tissue, is inherited as an autosomal dominant trait (A). The husband did not have ancestors with Marfan syndrome in the family, and the wife is heterozygous for this trait. Determine the genotypes of the parents and the likelihood of having a healthy baby
1. Genotypes and phenotypes P: Mother – Aa – t. it is indicated that she is heterozygous, the father – aa – t. there were no sick people in the family;
2. Genotypes and phenotypes of offspring: aa – healthy children 50% and Aa – Marfan syndrome 50%;
3. The probability of having healthy children is 50%.
Answer: mother – Aa, father – aa, probability – 50.
