In pathological processes, the number of lysosomes usually increases significantly in cells. This led to the idea that lysosomes can play an active role in cell death. However, it is known that upon rupture of the lysosomal membrane, the outgoing hydrolases lose their activity, since the cytoplasm is weakly alkaline. Explain what role lysosomes play in this case, based on the functional role of this organoid in the cell.
One of the functions of lysosomes is autolysis or autophagy. Currently, they tend to believe that the process of autophagocytosis is associated with the selection and destruction of altered, “broken” cellular components. In this case, lysosomes play the role of intracellular cleaners that control defective structures. In a specific case, the accumulation of lysosomes is associated with the performance of this function by enzymes – autolysis of dead cells.
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