In what other case, besides blood transfusion, is it necessary to take into account the Rh factor?

When a Rh-positive man and a Rh-negative woman marry, the fetus is likely to be Rh-positive too, so the mother begins to accumulate antibodies, anti-Rh substances, leading to the destruction of the erythrocytes of the unborn child. In the case of the first pregnancy, this is not so scary, and the birth of a second and third child is fraught with dangers, since upon repeated contact with the antigen, the woman’s body begins a violent reaction to produce antibodies and carrying a child will be impossible, or will affect his health. Artificial termination of the first pregnancy for an Rh negative woman can result in infertility.