Key points of the chromosome theory of heredity

The main provisions of the chromosome theory of heredity:
– Genes in the chromosomes are linearly arranged in a certain sequence. Allelic genes are located at the same loci of homologous chromosomes.
– Genes located on the same chromosome form a linkage group and are inherited together. The number of linkage groups is equal to the number of pairs of chromosomes.
– Gene linkage may be impaired as a result of crossing-over, which occurs during conjugation of homologous chromosomes in prophase I of meiosis.
– The crossover frequency is proportional to the distance between the genes: the greater the distance, the higher the crossover frequency and vice versa.
– For a unit of distance between linked genes, 1 morbid is taken – the distance at which crossing-over occurs with a probability of 1%.

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