In modern society, family marriages (marriages between cousins) are relatively rare. However, there are areas where, due to geographical, social, economic or other reasons, small contingents of the population for many generations live in isolation. In such isolated populations (the so-called isolates), the frequency of related marriages, for obvious reasons, is significantly higher than in ordinary “open” populations. Statistics show that in kinship parents, the probability of giving birth to children affected by various inherited ailments, or the frequency of early child mortality is tens, and sometimes even hundreds of times higher than in unrelated marriages. Family marriages are especially undesirable when there is a chance of spouses heterozygous for the same recessive harmful gene.
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