The most viable are people with sex chromosome abnormalities. Why are trisomy organisms in pairs 1-17 the least viable?

The most viable are people with sex chromosome abnormalities. Why are trisomy organisms in pairs 1-17 the least viable? Why, in this case, even embryos die at different stages of development?

Because during the formation of organs, organs begin to form incorrectly. Therefore, embryos that do not receive the correct development of the brain die, because they cannot develop normally.

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