What are the main points of the Oparin – Haldane hypothesis?

Key points:
1) the occurrence of organic substances;
2) the formation of simpler substances biopolymers (proteins, nucleic acids, etc.)
3) the emergence of primitive self-reproducing organisms.
In modern conditions, the emergence of living beings from inanimate nature is impossible. The abiogenic (i.e., without the participation of living organisms) occurrence of living matter was possible only in the conditions of the ancient atmosphere and the absence of living organisms. The composition of the ancient atmosphere included methane, ammonia, carbon dioxide, hydrogen, water vapor and other inorganic compounds. Under the influence of powerful electric discharges, ultraviolet radiation and high radiation, organic compounds could arise from these substances, which accumulated in the ocean, forming the “primary broth”. In the “primary broth”, multimolecular complexes — coacervates — were formed from biopolymers. Metal ions acting as the first catalysts fell into coacervate droplets from the external environment. From the huge amount of chemical compounds present in the “primary broth”, the most catalytic combinations of molecules were selected, which ultimately led to the appearance of enzymes. On the border between the coacervates and the external environment, lipid molecules were lined up, which led to the formation of a primitive cell membrane. At a certain stage, protein probionts included nucleic acids, creating single complexes, which led to the emergence of living properties such as self-reproduction, preservation of hereditary information and its transmission to subsequent generations. Probionts, in which metabolism was combined with the ability to reproduce themselves, can already be considered as primitive cells, the further development of which took place according to the laws of evolution of living matter.

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