When analyzing the nucleotide composition of bacteriophage M13 DNA, the following quantitative ratio of nitrogenous bases was found: A-23%, G-21%, T-36%, C-20%. How can you explain the reason that in this case the principle of equivalence established by Chargaff is not observed?
The reason is that bacteriophage M13 (like most phages) contains single-stranded DNA.
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