Why is agglutination dangerous? Why donor agglutinins are not taken into account when transfusing blood in small quantities? Why can’t large amounts of foreign blood be given?
1) as a result of sticking together erythrocytes cannot perform their function – transport of oxygen molecules
2) donor agglutinins are significantly diluted and lose the ability to agglutinate erythrocytes of the recipient
3) a large amount of donor agglutinins can lead to agglutination
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