How is blood serum different from plasma?

Blood plasma – the liquid part of the blood in which the shaped elements are suspended. Macroscopically, it is a homogeneous transparent or somewhat cloudy yellowish liquid that collects in the upper part of the vessel with blood after deposition of the shaped elements. Histologically, plasma is an intercellular substance of liquid blood tissue. Blood plasma consists of water in which substances are dissolved – proteins and other organic and mineral compounds. The main plasma proteins are albumin, globulins and fibrinogen. Nutrients (in particular glucose and lipids), hormones, vitamins, enzymes and intermediate and final metabolic products, as well as inorganic ions, are also dissolved in blood plasma. Blood serum is the liquid part of the blood without the formed elements and fibrin, which is formed during their separation during blood coagulation outside the body. Blood serum contains acquired immunity agents. Blood serum is obtained already outside the human body by differential centrifugation, as a result of which proteins and blood cells are precipitated.

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